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100 Lorazepam 1mg EU quaality treatment of reactive associated to anxiety neurosis or some somatic disorders. delivery UK 5 working days


LORAZEPAMUM Anxiar 1 mg is indicated for: the treatment of reactive associated to anxiety neurosis or some somatic disorders; bouts of anxiety; Prevention and treatment of delirium tremens; treatment of alcohol withdrawal syndrome.



Each tablet contains 1 mg lorazepam and excipients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, colloidal anhydrous silica, magnesium stearate.


Anxiar 1 mg is indicated for: the treatment of reactive associated to anxiety neurosis or some somatic disorders; bouts of anxiety; Prevention and treatment of delirium tremens; treatment of alcohol withdrawal syndrome. 
Access panic is not a therapeutic indication


Hypersensitivity to lorazepam, take other benzodiazepines or to any of the excipients, respiratory failure severe sleep apnea, severe hepatic insufficiency (risk of encephalopathy). Benzodiazepine in nursing mothers can cause sedative effects (lethargy, decreased tone) to infants. The administration of the product is contraindicated during lactation, if the use of the product is absolutely necessary, stop breastfeeding. The combination of several benzodiazepines, whatever the indication (anxiolytics and hypnotics) may increase the risk of addiction. Also after discontinuation may rebound to occur, manifested by exacerbating anxiety which required initiation of therapy, in the coming hours lorazepam anterograde amnesia can occur. In some people, benzodiazepines can cause paradoxical reactions, particularly in children and the elderly;agitation, aggression, irritability, tension, disorders of consciousness, abnormal behavior, automatic acts amnesia; they require discontinuation. Apart from the need of high doses of benzodiazepine ization. 

Administration method:

For all indications, treatment should be started with the lowest effective dose and the maximum dose should not be exceeded recomandola. 

- the first day of treatment - is recommended to unite many Anxiar 1mg tablet (0.5 mg lorazepam, morning and noon and Anxiar 1mg tablet (1 mg lorazepam) evening 
- the next day - the dose adjusted gradually Depending on the clinical course, the usual dose is 2-4 tablets 1 mg Anxiar (2-4 mg lorazepam) daily. In severe cases may require higher doses. 

Children over 6 years, elderly patients with renal impairment, patients with hepatic impairment is recommended to use a lower dose than that of adults, ie half the usual dose.Treatment duration should be as short as possible. Therapeutic indication should be reassessed regularly, especially in the absence of symptoms. In most patients, treatment duration should not exceed 8-12 weeks, including the period of dose reduction. In some cases, it may need further treatment. This forces the accurate assessment and repeated clinical status of the patient. 


Associated reactive anxiety neurosis or some somatic disorders: 4-12 weeks, including the period of dose reduction.

Depression Anxiety: short-term treatment. Prevention and treatment of delirium tremens: a few days. 

Alcohol withdrawal syndrome: 3-6 weeks, discontinuation should be done gradually, with decreasing doses over several weeks.

This formulation is applicable to children under 6 years.

Side effects:

Reactions occurring during lorazepam are dose dependent and individual sensitivity: EBRI state; fatigue, decreased alertness, sleepiness (especially elderly Ia); Muscle weakness. 
They can also occur: anterograde amnesia; paradoxical reactions in some patients - agitation, aggression, irritability, tension, impaired consciousness, abnormal behavior, automatic acts amnesia, psychological and physical dependence, even at therapeutic doses, the abstinence syndrome or rebound after discontinuation; rash, itching or not;changes in libido; respiratory depression.


All treatments with benzodiazepines, especially with prolonged use can produce psychological and physical dependence. 
Certain factors por favor the development of addiction: long duration; high dose; other existing history of drug dependence or not, including alcohol. 
discontinuing treatment abstinence syndrome may occur. Some call common and banal manifestations; insomnia, headache, anxiety marked, myalgia, muscle tension, irritability. Other events are rare: restlessness, confusion, exacerbated sensitivity to various stimuli (noise, light), depersonalization, hallucinations, seizures. 
Manifestations of abstinence syndrome may occur a few days after discontinuation.


Combinations not recommended with: 
- ethanol 
- potentiation of sedative effect of benzodiazepines, impaired vigilance can make dangerous driving or operating machinery. Concomitant use to be considered, with: - other depressants of central nervous system (analgesic and antitussive opioids - including methadone , barbilurice, sedative antidepressants, sedating antihistamines, other anxiolytics, neuroleptics, dionidina and substances closely related - increasing the central depressive effect may have important consequences, especially when driving vehicles or operating machinery; clozapine - increased risk of collapse with respiratory arrest and / or heart. 

Special precautions:


In patients with respiratory failure, it must consider the effect of respiratory depressant benzodiazepine (anxiety and agitation may be signs of decompensation of respiratory function and require hospitalization in an intensive care unit). Children In children, require very careful assessment report potential risk / benefit before prescribing; should be undertaken for periods as short as possible. 

The ability to drive and use machines 
intramuscular lorazepam is contraindicated to drivers of vehicles and those using machines.

Pregnancy and lactation:

Animal studies have shown that some benzodiazepines have teratogenic effects. 
In clinic, some of benzodiazepines has evoked a risk of birth defects. This risk has not been confirmed by subsequent epidemiological studies. The administration of lorazepam in doses in late pregnancy can cause weakness and respiratory distress in newborns soon after birth. After a few days - weeks after birth, can occur abstinence syndrome in newborns. As a result, benzodiazepines not to be used during the first trimester of pregnancy unless clearly necessary, in the last trimester of pregnancy is necessary to avoid the imposition of appropriate treatment. In case of ingestion of very high doses of lorazepam took less than an hour, we recommend inducing vomiting if the patient is conscious; otherwise, gastric lavage. If it is more than an hour of ingestion, give activated charcoal to reduce absorption. The administration of flumazenil may be useful for the diagnosis and / or treatment of benzodiazepine overdose accidentally or intentionally. 


In case of ingestion of very high doses, signs of overdose is manifested mainly by going deep sleep to coma, depending on the dose. In mild cases signs of mental confusion and lethargy. More serious cases can manifest itself ataxia, hypotonia, hypotension, respiratory depression, rarely death. The prognosis is favorable, the absence of association with other central depressive and drop titration, patients should be warned of the possibility of rebound phenomena. Benzodiazepines is not used to treat psychotic disorders and even depression that can be masked when used alone. In case of a history of dependence on alcohol, drugs or other substances, use of lorazepam should be done with great caution. Since benzodiazepine administration worsen symptoms of MG patients with this condition benzodiazepines is recommended only if absolutely necessary and under close supervision. 


Do not use after the expiration date printed on the packaging. 
Store the product at temperatures below 25 ° C in original packaging. 
Keep away from children.


ManufacturerGedeon Richter
Stock StatusOut of stock
Weight0.0 kg


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